Colts and Titans will play in a final regular season game on Sunday, September 29.
The Colts are 3-0 heading into the game against the New York Giants at Lucas Oil Stadium.
The Titans are 0-3.
The game will be broadcast live on ESPN2, the ESPN app and on the NFL Network.
The game will also be available to stream on NFL GamePass.
It is expected to air on ESPN3.
Titans quarterback Marcus Mariota has thrown for 4,096 yards and 23 touchdowns.
He has a career passer rating of 102.6 and has thrown 13 touchdowns in his last six games.
The Colts are 1-1 heading into this game.
The Patriots are 2-0.
The Titans have won four straight against Indianapolis.
The latest Around The NFL Podcast discusses the latest news and analysis from around the NFL.